The platform · how VitaCrypt works

Four pillars. One encrypted profile.

Most health tools do one of these. VitaCrypt does all four — and the value is in how they compound.

A unified six-stream data fabric; every recommendation cited to live science; fully homomorphic encryption so our servers never see your plaintext; and personalization down to your genotype and local environment. Here is how each one works.

Pillar 01 · Unified

Six streams, fused on your device — before anything is encrypted.

Unification doesn't happen on our servers. Your phone pulls each source, normalizes it into one schema, and only then encrypts the combined profile under your key. We only ever receive one ciphertext — never six plaintext feeds.

  1. 1
    Connect or upload

    Wearables stream through Terra API; DNA, microbiome and lab files are uploaded; environment is pulled from your location.

  2. 2
    Normalize on-device

    Different formats — VCF, FHIR, CSV, JSON — are mapped into one queryable health schema in local storage.

  3. 3
    Encrypt under your key

    The unified profile is encrypted with a key held in your iOS Keychain / Android Keystore. Plaintext never leaves the device.

What's connected — and when

SourceWhat it addsAvailability
GeneticsVariants that reshape every other signal — folate cycle, lipids, caffeine, methylationAt MVP launch23andMe / Ancestry upload
WearablesHRV, sleep stages, recovery, resting heart, activity loadAt MVP launchTerra API · Apple Watch, Oura, Whoop
EnvironmentPM2.5, ozone, pollen, UV — by your location, in real timeAt MVP launchPurpleAir / IQAir / OpenWeather
LifestyleStress, mood, diet, sleep quality via NIH-validated PROMIS short-formsAt MVP launchin-app check-ins
MicrobiomeGut composition → inflammation, nutrient absorption, diet responseUpload at MVPpartner API on roadmap
Labs & bloodCRP, ApoB, HbA1c, lipid panels — the objective check on the wearable signalUpload at MVPHL7/FHIR connectors 2027
Pillar 02 · Cited to live science

Every recommendation traces to a source — re-checked as new science lands.

Most apps bake in whatever the guidelines said the year they shipped. VitaCrypt re-queries the literature continuously, so a recommendation can change the week a relevant paper, GWAS hit, or guideline update appears.

How research-watch works under encryption

  1. 1
    The model reads only public science

    An agent continuously scans public literature and guidelines. It never touches your data — it works entirely on published papers.

  2. 2
    Matching happens under FHE

    Whether a finding applies to you is computed against your encrypted profile cryptographically — the model never sees your genotype or labs.

  3. 3
    The citation travels with the advice

    Each surfaced recommendation carries the source it rests on, graded by evidence strength.

What we actually query

We search PubMed (~40M indexed records) and the Cochrane Database of systematic reviews (~8,500 reviews), plus GWAS Catalog, ClinVar, and clinical guidance from USPSTF, WHO and NICE. "Cross-referenced" means we search these indexes for evidence relevant to your profile — not that 40M studies stand behind any one recommendation.

How a recommendation earns its citation

StrongestSystematic reviews & meta-analyses (Cochrane), grade A/B guidelines (USPSTF).
SupportingCohort studies, GWAS associations, mechanism papers.
FlaggedSingle studies / preprints — shown, but labelled preliminary.
Example · why "shift cardio to low-AQI hours"
A folate-cycle variant (MTHFR C677T) raises sensitivity to PM2.5-driven inflammation, so timing exertion away from pollution peaks matters more for this person.
Cited · PubMed PMC6068673 · meta-analysis
Pillar 03 · Encrypted compute

We compute on your biology without ever decrypting it.

Fully Homomorphic Encryption (FHE) lets a server run analysis on data that stays locked the whole time. The result comes back encrypted; only your key opens it — like a sealed box a mathematician can still do arithmetic inside.

Where the line is — honestly

Your device
  • Holds the key (Keychain / Keystore)
  • Encrypts the unified profile
  • Decrypts results — locally
Plaintext never leaves here.
ciphertext →← ciphertext
VitaCrypt server
  • Runs FHE compute on ciphertext
  • Holds reference data in clear (1000 Genomes panels, literature)
  • Never holds a decryption key
A breach yields mathematical noise.

Encryption and decryption run client-side — the pattern Zama shipped in its iOS FHE SDK (2025). The heavy compute is centralized FHE on our servers, not on your phone. We're targeting the Zama Concrete ML / TFHE stack; multi-party blind computing (Nillion) is on the roadmap as defense-in-depth, not in the MVP.

Is this real yet? The benchmark

Zama's published encrypted-DNA work (bounty #95, 2024) reached 96% accuracy on encrypted DNA ancestry classification — chromosome 22, 1000 Genomes — in about five minutes, with the query genome encrypted and the reference panel in clear. That's the honest scope today: ancestry-class inference, not whole-genome variant calling. It's the proof the primitive works at investigator-grade latency.

Architecture designed for HIPAA / GDPR alignment. Pre-MVP — no production health data yet.

Pillar 04 · Personalized

The same biology reads differently depending on your genes and where you live.

Generic advice optimizes for a median person who doesn't exist. VitaCrypt reads each signal against your genotype and local exposures — so the same air, the same HRV dip, the same lab value yields a different instruction for a different person.

How a protocol is built

  1. 1
    Inputs

    Genotype + current exposures (air, season, location) + physiology (HRV, sleep, labs).

  2. 2
    Interaction reasoning

    Gene × environment interactions are evaluated against the cited literature — under FHE.

  3. 3
    Action

    A small set of concrete, time-bound steps — each with its evidence attached.

The evidence behind the David example

MTHFR C677T × PM2.5

The folate-cycle variant blunts homocysteine clearance; ambient PM2.5 adds inflammatory load. Together they're linked to higher ischemic-heart and vascular risk.

PubMed · PMC6068673 — meta-analysis
APOE ε4 × PM2.5

ε4 carriers show a greater neuroinflammatory response to fine-particulate exposure — observed even in young adults — relevant to long-horizon cognitive risk.

PubMed · PMC10296707 — 2023

David is a composite case from the litepaper. Values are illustrative; the gene–environment methodology and citations are real.

If your biology is going to be read, it should be by something that can't see.

VitaCrypt opens to its first design partners in Q4 2026. Investors and prospective partners — reach out directly.